Laboratory
Select Publications
Marker-free characterization full-length transcriptomes of single live circulating tumor cell
Sarita Poonia, Anurag Goel, Smriti Chawla, Namrata Bhattacharya, Priyadarshini Rai, Yi Fang Lee, Yoon Sim Yap, Jay West, Ali Asgar Bhagat, Juhi Tayal, Anurag Mehta, Gaurav Ahuja, Angshul Majumdar*, Naveen Ramalingam*, Debarka Sengupta*
Microfluidic system-based time-course tracking of physical proximity between cells and its effect on gene expression for elucidating live single cancer-immune cell interactions
Bianca C. T. Flores, Smriti Chawla, Ning Ma, ..., Naveen Ramalingam*, Debarka Sengupta*, Stefanie Jeffery*
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Gene expression based inference of cancer drug sensitivity
Smriti Chawla, Anja Rockstroh, Melanie Lehman, Ellca Ratther, Atishay Jain, Anuneet Anand, Apoorva Gupta, Namrata Bhattacharya, Sarita Poonia, Priyadarshini Rai, Nirjhar Das, Angshul Majumdar, Jayadeva Jayadeva, Gaurav Ahuja, Brett Hollier, Colleen Nelson*, Debarka Sengupta*
Nature Comms. 13, Article number: 5680 (2022)
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A new deep learning technique reveals the exclusive functional contributions of individual cancer mutations
Prashant Gupta, Aashi Jindal, Gaurav Ahuja, Jayadeva*, Debarka Sengupta*
Artificial intelligence uncovers carcinogenic human metabolites
Aayushi Mittal, Sanjay Kumar Mohanty, Vishakha Gautam, Sakshi Arora, Sheetanshu Saproo, Ria Gupta, Roshan Sivakumar, Prakriti Garg, Anmol Aggarwal, Padmasini Raghavachary, Nilesh Kumar Dixit, Vijay Pal Singh, Anurag Mehta, Juhi Tayal, Srivatsava Naidu, Debarka Sengupta* & Gaurav Ahuja*
Nature Chem. Bio. https://doi.org/10.1038/s41589-022-01110-7
Quantification of Age-Related Decline in Transcriptional Homeostasis
Krishan Gupta, Princey Yadav, Sidrah Maryam, Gaurav Ahuja*, Debarka Sengupta*
Modeling expression ranks for noise-tolerant differential expression analysis of scRNA-seq data
Krishan Gupta, Manan Lalit, Aditya Biswas, Chad D. Sanada, Cassandra Greene, Kyle Hukari, Ujjwal Maulik, Sanghamitra Bandyopadhyay, Naveen Ramalingam, Gaurav Ahuja, Abhik Ghosh, Debarka Sengupta*
Genome Res. 2021 Apr; 31(4): 689–697.
OdoriFy: A conglomerate of artificial intelligence–driven prediction engines for olfactory decoding
Ria Gupta, Aayushi Mittal, Vishesh Agrawal, Sushant Gupta, Krishan Gupta, Rishi Raj Jain, Prakriti Garg, Sanjay Kumar Mohanty, Riya Sogani, Harshit Singh Chhabra, Vishakha Gautam, Tripti Mishra, Debarka Sengupta, Gaurav Ahuja*
The Cellular basis of loss of smell in 2019-nCoV-infected individuals
Krishan Gupta, Sanjay Kumar Mohanty, Aayushi Mittal, Siddhant Kalra, Suvendu Kumar, Tripti Mishra, Jatin Ahuja, Debarka Sengupta*, Gaurav Ahuja*
UniPath: a uniform approach for pathway and gene-set based analysis of heterogeneity in single-cell epigenome and transcriptome profiles
Smriti Chawla, Sudhagar Samydurai, Say Li Kong, Zhengwei Wu, Zhenxun Wang, Wai Leong Tam, Debarka Sengupta*, Vibhor Kumar*
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Machine-OlF-Action: A unified framework for developing and interpreting machine-learning models for chemosensory research
Anku Gupta, Mohit Choudhary, Sanjay Kumar Mohanty, Aayushi Mittal, Krishan Gupta, Aditya Arya, Suvendu Kumar, Nikhil Katyayan, Nilesh Kumar Dixit, Siddhant Kalra, Manshi Goel, Megha Sahni, Vrinda Singhal, Tripti Mishra, Debarka Sengupta*, Gaurav Ahuja*
Molecular signature comprising 11 platelet-genes enables accurate blood-based diagnosis of NSCLC
Chitrita Goswami, Smriti Chawla, Deepshi Thakral, Himanshu Pant, Pramod Verma, Prabhat Singh Malik, Jayadeva, Ritu Gupta*, Gaurav Ahuja*, Debarka Sengupta*
Integrative Analysis and Machine Learning based Characterization of Single Circulating Tumor Cells
Arvind Iyer, Krishan Gupta, Shreya Sharma, Kishore Hari, Yi Fang Lee, Neevan Ramalingam, Yoon Sim Yap, Jay West, Ali Asgar Bhagat, Balaram Vishnu Subramani, Burhanuddin Sabuwala, Tuan Zea Tan, Jean Paul Thiery, Mohit Kumar Jolly, Naveen Ramalingam*, Debarka Sengupta*
Improved dropClust R package with integrative analysis support for scRNA-seq data
Debajyoti Sinha, Pradyumn Sinha, Ritwik Saha, Sanghamitra Bandyopadhyay*, Debarka Sengupta*
Staging System to Predict the Risk of Relapse in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation
Chitrita Goswami, Sarita Poonia, Lalit Kumar*, Debarka Sengupta*
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Discovery of rare cells from voluminous single cell expression data
Aashi Jindal, Prashant Gupta, Jayadeva*, Debarka Sengupta*
CellAtlasSearch: a scalable search engine for single cells
Divyanshu Srivastava, Arvind Iyer, Vibhor Kumar*, Debarka Sengupta*
dropClust: efficient clustering of ultra-large scRNA-seq data
Debajyoti Sinha, Akhilesh Kumar, Himanshu Kumar, Sanghamitra Bandyopadhyay*, Debarka Sengupta*